MLB Schedule – April 22–26, 2025

MLB Schedule & Probable Pitchers – April 22–26, 2025

Stay ahead of the action with this daily MLB matchup preview featuring starting pitchers, team records, and stadiums for April 22–25. Ideal for fans, fantasy baseball players, and sports bettors looking for up-to-date insight.

Tuesday, April 22, 2025

New York Yankees vs. Cleveland Guardians

• 📍 Progressive Field, Cleveland, OH
• 🕐 11:10 PM ET
• 📊 Yankees (14-96-5 Away) | Guardians (13-96-1 Home)
• ⚾ Starting Pitchers:
• Yankees: Will Warren (1-0, 5.17 ERA)
• Guardians: Tanner Bibee (1-2, 5.85 ERA)

Cincinnati Reds vs. Miami Marlins

• 📍 loanDepot Park, Miami, FL
• 🕐 11:40 PM ET
• 📊 Reds (11-125-6 Away) | Marlins (10-127-7 Home)
• ⚾ Starting Pitchers:
• Reds: Nick Martinez (0-3, 6.00 ERA)
• Marlins: Edward Cabrera (0-1, 6.52 ERA)

San Diego Padres vs. Detroit Tigers

• 📍 Comerica Park, Detroit, MI
• 🕐 11:45 PM ET
• 📊 Padres (16-74-6 Away) | Tigers (14-99-2 Home)
• ⚾ Starting Pitchers:
• Padres: Nick Pivetta (3-1, 1.57 ERA)
• Tigers: Jack Flaherty (1-1, 2.53 ERA)

Wednesday, April 23, 2025

Philadelphia Phillies vs. New York Mets

• 📍 Citi Field, Queens, NY
• 🕐 12:10 AM ET
• 📊 Phillies (13-104-6 Away) | Mets (16-710-1 Home)
• ⚾ Starting Pitchers:
• Phillies: Cristopher Sánchez (2-0, 2.96 ERA)
• Mets: Griffin Canning (2-1, 3.43 ERA)

St. Louis Cardinals vs. Atlanta Braves

• 📍 Truist Park, Atlanta, GA
• 🕐 12:15 AM ET
• 📊 Cardinals (9-141-10 Away) | Braves (9-137-2 Home)
• ⚾ Starting Pitchers:
• Cardinals: Andre Pallante (2-1, 3.22 ERA)
• Braves: TBA

Thursday, April 24, 2025

Boston Red Sox vs. Chicago White Sox

• 📍 Guaranteed Rate Field, Chicago, IL
• 🕐 12:10 AM ET
• 📊 Red Sox (10-123-9 Away) | White Sox (10-115-4 Home)
• ⚾ Starting Pitchers:
• Red Sox: Brayan Bello (3-0, 3.38 ERA)
• White Sox: Garrett Crochet (1-1, 2.00 ERA)

Los Angeles Angels vs. Houston Astros

• 📍 Minute Maid Park, Houston, TX
• 🕐 12:10 AM ET
• 📊 Angels (8-132-3 Away) | Astros (11-116-5 Home)
• ⚾ Starting Pitchers:
• Angels: Chase Silseth (1-1, 4.87 ERA)
• Astros: Spencer Arrighetti (0-2, 8.27 ERA)

Tampa Bay Rays vs. Chicago Cubs

• 📍 Wrigley Field, Chicago, IL
• 🕐 2:20 PM ET
• 📊 Rays (14-82-5 Away) | Cubs (11-111-6 Home)
• ⚾ Starting Pitchers:
• Rays: Taj Bradley (2-1, 2.93 ERA)
• Cubs: Justin Steele (1-2, 4.43 ERA)

Friday, April 25, 2025

Texas Rangers vs. Oakland Athletics

• 📍 Oakland Coliseum, Oakland, CA
• 🕐 3:37 PM ET
• 📊 Rangers (12-113-6 Away) | Athletics (11-126-4 Home)
• ⚾ Starting Pitchers:
• Rangers: Dane Dunning (3-1, 3.09 ERA)
• Athletics: Joe Boyle (1-1, 4.15 ERA)

Baltimore Orioles vs. Los Angeles Dodgers

• 📍 Dodger Stadium, Los Angeles, CA
• 🕐 10:10 PM ET
• 📊 Orioles (12-93-6 Away) | Dodgers (16-84-6 Home)
• ⚾ Starting Pitchers:
• Orioles: John Means (2-1, 4.13 ERA)
• Dodgers: Yoshinobu Yamamoto (3-1, 2.70 ERA)

Arizona Diamondbacks vs. Seattle Mariners

• 📍 T-Mobile Park, Seattle, WA
• 🕐 10:10 PM ET
• 📊 D-backs (9-129-7 Away) | Mariners (10-131-8 Home)
• ⚾ Starting Pitchers:
• Diamondbacks: Slade Cecconi (1-1, 3.54 ERA)
• Mariners: Bryce Miller (3-0, 1.85 ERA)

Toronto Blue Jays vs. Colorado Rockies

• 📍 Coors Field, Denver, CO
• 🕐 10:10 PM ET
• 📊 Blue Jays (11-124-7 Away) | Rockies (8-142-4 Home)
• ⚾ Starting Pitchers:
• Blue Jays: Kevin Gausman (1-2, 3.63 ERA)
• Rockies: Kyle Freeland (1-2, 6.75 ERA)

San Francisco Giants vs. Milwaukee Brewers

• 📍 American Family Field, Milwaukee, WI
• 🕐 8:10 PM ET
• 📊 Giants (13-101-5 Away) | Brewers (12-106-6 Home)
• ⚾ Starting Pitchers:
• Giants: Blake Snell (2-1, 4.76 ERA)
• Brewers: Freddy Peralta (2-1, 3.24 ERA)

Minnesota Twins vs. Kansas City Royals

• 📍 Kauffman Stadium, Kansas City, MO
• 🕐 8:10 PM ET
• 📊 Twins (11-110-5 Away) | Royals (12-113-7 Home)
• ⚾ Starting Pitchers:
• Twins: Joe Ryan (3-0, 2.85 ERA)
• Royals: Cole Ragans (2-1, 3.40 ERA)

Saturday, April 26, 2025

Philadelphia Phillies vs. New York Mets

• 📍 Citi Field, Queens, NY
• 🕐 4:10 PM ET
• 📊 Phillies (14-104-6 Away) | Mets (17-710-1 Home)
• ⚾ Starting Pitchers:
• Phillies: Zack Wheeler (2-2, 3.21 ERA)
• Mets: Kodai Senga (3-1, 2.95 ERA)

Boston Red Sox vs. Chicago White Sox

• 📍 Guaranteed Rate Field, Chicago, IL
• 🕐 2:10 PM ET
• 📊 Red Sox (11-123-9 Away) | White Sox (11-115-4 Home)
• ⚾ Starting Pitchers:
• Red Sox: Kutter Crawford (2-1, 3.07 ERA)
• White Sox: Erick Fedde (1-2, 4.21 ERA)

St. Louis Cardinals vs. Atlanta Braves

• 📍 Truist Park, Atlanta, GA
• 🕐 7:20 PM ET
• 📊 Cardinals (10-141-10 Away) | Braves (10-137-2 Home)
• ⚾ Starting Pitchers:
• Cardinals: Lance Lynn (1-3, 5.76 ERA)
• Braves: Max Fried (2-1, 3.11 ERA)

Cincinnati Reds vs. Miami Marlins



• 📍 loanDepot Park, Miami, FL
• 🕐 4:10 PM ET
• 📊 Reds (12-125-6 Away) | Marlins (11-127-7 Home)
• ⚾ Starting Pitchers:
• Reds: Hunter Greene (2-2, 4.02 ERA)
• Marlins: Jesús Luzardo (1-3, 4.88 ERA)