Kansas City Royals 3, Tampa Bay Rays 1
- Winning Pitcher: Michael Lorenzen
- Losing Pitcher: Taj Bradley
- Save: Carlos Estevez
Boston Red Sox 10, Toronto Blue Jays 2
- Winning Pitcher: Garrett Crochet
- Losing Pitcher: Bowden Francis
- Highlights: Five home runs by Boston, including a three-run shot by Wilyer Abreu.
New York Mets 8, Arizona Diamondbacks 3
- Winning Pitcher: David Peterson
- Losing Pitcher: Eduardo Rodriguez
Milwaukee Brewers 7, Chicago White Sox 2
- Winning Pitcher: Freddy Peralta
- Losing Pitcher: Bryse Wilson
Texas Rangers 15, Oakland Athletics 2
- Winning Pitcher: Jacob deGrom
- Losing Pitcher: Jacob Lopez
- Save: Dane Dunning
Houston Astros 6, Detroit Tigers 4
- Winning Pitcher: Bennett Sousa
- Losing Pitcher: Reese Olson
Atlanta Braves 8, Colorado Rockies 2
- Winning Pitcher: AJ Smith-Shawver
- Losing Pitcher: German Marquez
Seattle Mariners 5, Los Angeles Angels 3
- Winning Pitcher: Bryce Miller
- Losing Pitcher: Jack Kochanowicz
- Save: Andres Munoz
San Diego Padres 7, San Francisco Giants 4
- Winning Pitcher: Nick Pivetta
- Losing Pitcher: Logan Webb
- Save: Robert Suarez
Los Angeles Dodgers 15, Miami Marlins 2
- Winning Pitcher: Matt Sauer
- Losing Pitcher: Sandy Alcantara
Chicago Cubs 9, Pittsburgh Pirates 0
- Winning Pitcher: Shōta Imanaga
- Highlights: Four home runs by the Cubs, including Seiya Suzuki and Dansby Swanson.
New York Yankees 15, Baltimore Orioles 3
- Highlights: Back-to-back-to-back home runs to open the game; Carlos Rodón took a perfect game into the sixth inning.
